Regional Genetics Service

Address

Molecular Genetics Laboratory

Royal Devon & Exeter Foundation NHS Trust

Barrack Road

Exeter

Devon

EX2 5DW

 

Contact 1

 Dr Sian Ellard

Contact 2

 Dr Carolyn Tysoe

Contact 3

 Mrs Chris Parkes – Administrator

Telephone 1

 +44 (0)1392 402910

Telephone 2

 +44 (0)1392 402946

Fax:

 +44 (0)1392 402946

Email 1

 mailto:sian.ellard@rdeft.nhs.uk

Email 2

 mailto:carolyn.tysoe@rdeft..nhs.uk

Email 3

 mailto:christine.parkes@rdeft.nhs.uk

General email

 mailto:moleculargenetics@rdeft.nhs.uk

Home page   www.rdehospital.nhs.uk/prof/molecular_genetics/default.htm

 

Services offered: 14/05/08 update 

Disease

OMIM

UKGTN service*

Alagille syndrome (JAG1)

118450

YES

CADASIL (NOTCH3)

125310

YES

CFEOM type 1 (KIF21A)

135700

YES

Chondrodysplasia punctata AR (PEX7)

215100

YES

Chondrodysplasia punctata XL (EBP)

302960

YES

Chondrodysplasia punctata CDPX1 (ARSE)

302950

YES

Chondrodysplasia punctata RCDP2 (DHAPAT)

222765

YES

Chondrodysplasia punctata RCDP3 (AGPS)

600121

YES

Chimaerism

 

YES

Cyclin D1 overexpression

 

 

Cystic fibrosis ABCC7 (CFTR)

219700

 

Duane radial ray syndrome Okihiro syndrome (SALL4)

607323

YES

Emery Dreifuss Muscular Dystrophy (LMNA)

181350

YES

Factor V Leiden (FVL)

 

YES

Familial Isolated Pituitary Adenoma (AIP)

102200

YES

Familial medullary thyroid cancer (RET)

155240

YES

Familial partial lipodystrophy (LMNA)

151660

YES

Haemochromatosis (HFE)

235200

YES

Hirschprung disease (RET)

142623

YES

Horizontal gaze palsy with progressive scoliosis (ROBO3)

607313

YES

Hyperinsulinism dominant (GCK)

602820

YES

Hyperinsulinism recessive (ABCC8/KCNJ11)

601820

YES

Hyperinsulinism recessive (HADH)

609975

YES

Hyperinsulinism-hyperammonemia syndrome (GLUD1)

606762

YES

Hyperthyroidism (TSHR)

609152

YES

Hypophosphaemic rickets AD (FGF23)

193100

YES

Hypophosphaemic rickets XL (PHEX)

307800

YES

Hypophosphaemic rickets AR (DMP1)

241530

YES

Hypophosphaemic rickets with hypercalciuria (SLC34A3)

241530

YES

IPEX syndrome (FOXP3)

304790

YES

Mandibuloacral Dyslasia (ZMPSTE24)

608612

YES

Maternally inherited diabetes & deafness (MIDD)

520000

YES

Maturity onset diabetes of the young (GCK)

606391

YES

Maturity onset diabetes of the young (HNF1A)

606391

YES

Maturity onset diabetes of the young (HNF4A)

606391

YES

Maturity onset diabetes of the young (IPF1)

606391

YES

Maturity onset diabetes of the young (NEUROD1)

606391

YES

Multiple endocrine neoplasia type 1 (MEN1)

131100

YES

Multiple Endocrine Neoplasia type 1 – like syndrome (CDKN1B)

610755

 

Multiple endocrine neoplasia type 2A MEN2A (RET)

171400

YES

Multiple endocrine neoplasia type 2B MEN2B (RET)

162300

YES

Myeloproliferative disorders (JAK2)

 

YES

Permanent neonatal diabetes (KCNJ11)

606176

YES

Permanent neonatal diabetes (ABCC8)

606176

YES

Prothrombin (FII)

137920

YES

Renal cysts & diabetes (HNF1b)

137920

YES

Restrictive Dermopathy (ZMPSTE24)

275210

YES

Spondylocostal Dysostosis type 1 (DLL3)

277300

YES

Spondylocostal Dysostosis type 2 (MESP2)

608681

YES

Thiamine responsive megaloblastic anaemia TRMA (SLC19A2)

249270

YES

Wollcott-Rallison syndrome (EIF2AK3)

226930

YES

B-cell clonality

 

 

T-cell clonality

 

 

t:(9:22)

 

 

t:(11:14)

 

 

t:(14:18)

 

 

t:(15:17)

 

 

 

 

 

*Services offered outside main commissioning area geographical

boundaries under the UK specialist Genetic Testing Network - enquire to the laboratory on costs.