All Wales Molecular Genetic Laboratory

Address

 Molecular Genetics, Institute of Medical Genetics, Cardiff and Vale NHS Trust, Heath Park, Cardiff. CF14 4XW.

Contact 1

Rachel Butler

Contact 2

Laz Lazarou

Contact 3

 

Telephone 1

02920 742641

Telephone 2

02920 744333

Telephone 3

 

Fax:

 02920 744043

Email 1

Rachel.butler@cardiffandvale.wales.nhs.uk

Email 2

laz.lazarou@cardiffandvale.wales.nhs.uk

Email 3

 

Home page

 http://www.wales.nhs.uk/AWMGS

 

 

Services offered: 30/04/2008 update    

Disease

OMIM

UKGTN service*

Autosomal Dominant Polycystic Kidney Disease (types 1 and 2) - Adult

Linkage only

601313 173910

 

YES

ARX

300432, 308350

YES

Autosomal Recessive Polycystic Kidney disease, Infantile (linkage and mutation screening)

263200

 

YES

Cystic Fibrosis

219700

 

Deafness, non-syndromic sensorineural; DFNB1 (GJB2 / GJB6) 220290 YES

Duchenne / Becker  Muscular Dystrophy

310200 300376

 

Ectodermal Dysplasia - Anhydrotic

305100 224900

YES

Familial Adenomatous Polyposis Coli

175100

 

Familial breast / ovarian cancer 

114480

 

Fascio scapulo humoral Dystrophy

158900

YES

Fetal sexing

 

 

Fragile X (A) disease

309550

 

Fragile X (E) disease

309548

YES

Friedreich’s ataxia

229300

 

HNPCC

120435 120436 158320

 

Huntington disease

143100

 

Infantile spasms syndrome, X-linked (ISSX)

308350

YES

Lissencephaly (LIS-1 gene)

607432

YES

Lissencephaly -XL (DCX gene)

300121 300067

YES

MUTYH (multiple colorectal adenomas)

604933

YES

Myotonic Dystrophy 1

160900

 

Neurofibromatosis Type 1

162200

YES

Optic atrophy, autosomal dominant (OPA1) 165500 YES
Parkinsons disease, Young onset 168600 YES

PROMM (Myotonic dystrophy 2)

116955

YES

Rett Syndrome

312750

YES

Spinal Cerebellar Ataxia types 1, 2, 3 (Machado joseph), 6 & 7

164400 183090 109150 183086 164500

 

Tuberous Sclerosis Type 1/2

191100 191092

YES

 Xq28 XLMR syndrome; duplications of MECP2 gene

 300260

 YES

     

*Services offered outside main commissioning area geographical

boundaries under the UK specialist Genetic Testing Network - enquire

to the laboratory on costs.

 

*Services offered outside main commissioning area geographical

boundaries under the UK specialist Genetic Testing Network - enquire

to the laboratory on costs.